Shiping Liu

Research Overview

My group is committed to integrating interdisciplinary knowledge from physics, computer science, and mathematics to advance research in multi-omics big data within the life sciences. Our mission is to unravel the complexities of biological systems, including brain science, tumor immunology, and the dynamic evolution of organ function across species.

Research Areas

1. Biocomputing

Applying interdisciplinary scientific knowledge and cutting-edge AI large model technologies, integrating multi-omics big data such as genomics, single-cell analysis, spatial transcriptomics, and epigenomics, to decipher the molecular and cellular dynamics mechanisms underlying critical life processes.

2. Evolutionary Developmental at Cellular and Functional Levels

Focusing on understanding the spatiotemporal dimensions of the central dogma (from the central dogma to spatiotemporal principles), we develop novel computational methods for studying evolutionary development at molecular, cellular, and structural levels. This includes exploring the mechanisms of tissue and organ development and investigating the principles of structure and function evolution.

3. Brain Science and Cancer Research

We construct cell atlases of brain tissues and tumor microenvironments, study the diversity of cell types and spatial structures in the nervous and immune systems, and explore the regulatory mechanisms of cell migration and differentiation.

4. Comparative Genomics

Through genomic and population genetic analyses, we investigate the genetic mechanisms underlying species adaptability and changes in population structure.

Join Our Research

We invite you to join our research group to explore the frontiers of science and drive innovation in life sciences. Together, let's embark on this exciting journey of discovery!